Buy Testosterone Enanthate Injections Online
Testosterone enanthate is an injectable testosterone supplement that is usually administered to treat low testosterone and other symptoms of hypogonadism in males. It is a slow-release oil-based ester that can be administered either intramuscularly or subcutaneously, depending on the health care provider’s preference or the individual receiving the injection. It was first used clinically as a treatment of low testosterone in 1937, and its use by men has since then significantly increased in popularity.
Mechanism of Action
Testosterone exerts its actions in the body primarily by means of its binding to and interaction with androgen receptors. In tissues within the body, the testosterone secreted by the testes is converted into a more potent metabolite known as dihydrotestosterone (DHT); this conversion of testosterone to its more active form is facilitated by the cytoplasmic enzyme known as 5 alpha-reductase. DHT then binds to the androgen receptors inside the cytoplasm of the target cells and forms a DHT-receptor complex. After the formation of the DHT complex, it passes into the nucleus of the target cells, where it binds to the relevant nucleotide sequences on the chromosomal DNA, which then results in the synthesis of the relevant proteins by nuclear transcription.
A second pathway by which testosterone also acts in the body is through its conversion into estradiol; the amount of testosterone that follows this pathway is considerably less than when involving DHT synthesis. In this pathway, free testosterone is converted by the cytochrome P-450 enzyme aromatase into estradiol. The estradiol that is produced then interacts with the estrogen receptors within the cells and then begins to exert its effects in the development and maintenance of bone density.
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